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applied separations is the world leader in supercritical fluids, separations, and extractions. in addition to being a manufacturer of a full line of supercritical fluid systems for all markets with systems ranging in size from analytical scale to pilot plants to full scale production, applied separations also has expertise in solid phase extraction (spe) and accelerated solvent extraction (ase), also known as pressurized solvent extraction (pse) and pressurized fluid extraction.